I needed a solution for making an application which is native 32b to “discuss” with a 64b client. The client is creating a shared memory in which some data is saved. The server needs to process the data. Amazon: Bestsellers Electronics and Photo Here is how MSDN describes the problem: Running 32-bit Applications (on 64-bit OS): http://msdn.microsoft.com/en-us/library/aa384249(VS.85).aspx And my problem is addresses here: http://msdn.microsoft.com/en-us/library/aa384203(VS.85).aspx Interprocess Communication Amazon: Bestsellers Electronics and Photo The following techniques can be used for communication between 32- and 64-bit applications: * Handles to named objects such as mutexes, semaphores, and file handles can all be shared. * Handles to windows (HWND) can be shared. * RPC. * COM LocalServers. * Shared memory can be used if the contents of the shared memory are not pointer-dependent. * The CreateProcess and ShellExecute functions can launch 32-bit and 64-bit processes from either 32-bit or 64-bit processes. Amazon: Bestsellers Electronics and Photo